The 13th World Congress of Regenerative Medicine & Stem Cell (RMSC-2019)

Program

Time: November 1- November 3, 2019

Venue: Dalian International Conference Center (DICC), Dalian, China

Registration

Time: 08:30-18:00, October 31, 2019 (Thursday); Place: Lobby, 1st Floor, DICC

Time: 18:00-22:00, October 31, 2019 (Thursday); Place: Lobby, 1st Floor, The Hilton Dalian

Opening Ceremony and Keynote Forum

Opening Ceremony

Time: 09:00-09:30, November 1, 2019 (Friday); Place: Room 302, 3rd Floor, DICC

Keynote Forum
Time: 09:30-11:15, November 1, 2019 (Friday); Place: Room 302, 3rd Floor, DICC

Moderator	*Dr. Jürgen Hescheler,* Professor, University of Cologne; Chairman, The German Society for Stem Cell Research, Germany

09:30-09:35	Chair’s Introduction
09:35-10:00	Title: Pluripotent Stem Cells: The All-rounders for Research and Medicine *Dr. Jürgen Hescheler,* Chairman, The German Society for Stem Cell Research, Germany
10:00-10:25	Title: An Introduction to the Tools Available to Determine Suitability of Serum for Use in Cell Culture Dr. Rosemary J. Versteegen, CEO, International Serum Industry Association, USA
10:25-10:50	*Title:* Clinical Research Progress of Stem Cell Therapeutics for Cerebral Palsy *Dr. Jing Liu,* Dean, Dalian Innovation Institute of Stem Cell and Precision Medicine, China
10:50-11:15	*Title:* Can Cancer Cells be Transformed into Normal Cells Using A Stem Cell Strategy? *Dr. Jianjun Wang,* Professor, Wayne State University, USA

High-end Dialogue
Time: 11:20-12:00, November 1, 2019 (Friday); Place: Room 302, 3rd Floor, DICC

Moderator	*Dr. Chuanjun Liu,* Head, The Plastic Surgery and Anti-aging of Dali University, China

*Dr. Jürgen Hescheler,* Chairman, The German Society for Stem Cell Research, Germany
*Dr. Abhijit Bopardikar,* Director, ReeLabs Private Limited; Joint Secretary, Stem Cell Society of India, India
*Dr. Nam-Sun Paik,* Director, Ewha Womans University Cancer Center Hospital for Women, Korea
*Dr. Jianjun Wang,* Tenured Professor, Medical College of Wayne State University, USA; Chief Scientist, Fuent Biotechnology Co. Ltd. (Shanghai), China
*Dr. Yue-Jin Yang,* Professor,Vice President, National Center of Cardiovascular Diease, Fuwai Hospital, China

RMSC 01: Stem Cell Biology and Interdisciplinary Research
Time: 13:30-17:10, November 1, 2019 (Friday); Place: Room 615&616, 6th Floor, DICC

Chair	*Dr. Guo-Ping Zhou,* Professor, Guangxi Academy of Sciences, China
Co-Chair	*Dr. Takayasu Ohtake,* Vice President, Shonan Kamakura General Hospital, Japan

13:30-13:35	Chair’s Introduction
13:35-13:55	*Title:* Tumor Suppressor WWOX is a Potent Regulator of Stem Cell Differentiation *Dr. Nan-Shan Chang,* Professor, National Cheng Kung University, Taiwan China
13:55-14:15	Title: CRISPR Tools Development for Molecular Oncology and Regenerative Medicine Dr. Dmitry Guschin, Senior Research Scientist, Moscow Institute of Physics and Technology, Russia
14:15-14:35	*Title:* The Intrinsic Relationship between Structure and Function of the Sialyl-Transferase ST8Sia Family Members *Dr. Guo-Ping Zhou,* Professor, Guangxi Academy of Sciences, China
14:35-14:55	Title: The Establishment of in Vitro System Based on AGM-S3 Co-culture for Drug Screening of Traditional Herb Medicine that Stimulate Hematopoiesis *Dr. Bo Chen,* Associate Professor, Chinese Academy of Medical Sciences & Peking Union Medical College, China
14:55-15:15	Title: Chitosan/Silk Fibroin Modified Nanofibrous Patches with Mesenchymal Stem Cells Prevent Heart Remodeling Post-Myocardial Infarction in Rats Dr. Jiangwei Chen, Physician, Xijing Hospital of Forth Military Medical University, China
15:15-15:30	Coffee Break
15:30-15:50	*Title:* High Efficacy of Autologous Granulocyte Colony-Stimulating Factor-Mobilized Peripheral Blood CD34 Positive Cell Transplantation for Hemodialysis Patients with Critical Limb Ischemia *Dr. Takayasu Ohtake,* Vice President, Shonan Kamakura General Hospital, Japan
15:50-16:10	*Title:* Enrichment Differentiation of Human Induced Pluripotent Stem Cells into Sinoatrial Node-Like Cells by Combined Modulation of Bmp, Fgf and Ra Signaling Pathway Dr. Rui Zhou, Associate Professor, Southwest Medical University, China
16:10-16:30	Title: Human Amniotic Epithelial Stem Cells-Derived Exosomes Promote Neuronal Differentiation of Mouse Neural Stem Cells Dr. Huiming Xu, Associate Professor, Shanghai Jiao Tong University, China
16:30-16:50	Title: Arrangement of Human Cell Metaphase Chromosomes on the Equatorial Plat Dr. Tao Jiang, Chief, The Second Affiliated Hospital of Nanjing University of Chinese Medicine, China
16:50-17:10	Title: Is That Your Patient in the Incubator? Controlling the Stem Cell Environment *Dr. Alicia D. Henn,* CSO, BioSpherix, Ltd., USA

RMSC 02: Tissue Engineering and Regenerative Medicine
Time: 13:30-16:30, November 1, 2019 (Friday); Place: Room 617&618, 6th Floor, DICC

Chair	*Dr. Issa Salim,* Founder, Medical Center of Bioresonance in Rashid Hospital, United Arab Emirates
Co-Chair	*Dr. Dingding Zhang,* Professor, University of Electronic Science and Technology of China and Sichuan Provincial People Hospital, China

13:30-13:35	Chair’s Introduction
13:35-13:55	Title: hUCMSC Pretreated with Angiotensin-II Attenuate Injury via Enhancing Angiogenesis *Dr. Jing Yang,* Physician, Zhejiang University School of Medicine, China
13:55-14:15	Title: Development of Dual Delivery Antituberculotic System Containing Rifapentine Microspheres and Adipose Stem Cells Seeded in Hydroxyapatite/tricalcium Phosphate for Treating Infections and Promoting Bone Formation Dr. Qiuzhen Liang, Physician, The First Affiliated Hospital of Xinjiang Medical University, China
14:15-14:35	*Title:* Detection of Symptom Causes through Multiple Channel Treatment Dr. Issa Salim, Founder, Medical Center of Bioresonance in Rashid Hospital, United Arab Emirates
14:35-14:55	*Title:* Design based Challenges in Development of Biomaterials and Bioadhesives for Future Clinic Dr. Himansu Sekhar Nanda, Assistant Professor, Indian Institute of Information Technology Design and Manufacturing Jabalpur, India
14:55-15:15	*Title:* Evaluation of Long Intergenic Noncoding RNA MALAT1 in Patients with Lung Carcinoma Dr. Dingding Zhang, Professor, University of Electronic Science and Technology of China and Sichuan Provincial People Hospital, China
15:15-15:30	Coffee Break
15:30-15:50	*Title:* CAMKs Support Development of Acute Myeloid Leukemia Dr. Li Wang, Assistant Professor, Dalian University of Technology, China
15:50-16:10	Title: Effects and Mechanism of lncRNA Vof-16 on Nerve Repair after Spinal Cord Injury Dr. Hongfu Wu, Vice President, Dongguan-Guangdong Medical University Institute of Stem Cell and Regeneration Technology Transformation, China
16:10-16:30	*Title:* Metformin Induces Apoptosis in Mesenchymal Stromal Cells and Dampens Their Therapeutic Efficacy in Infarcted Myocardium Dr. Xiang Ao, Army Medical University, China

RMSC 03: Top Innovative Regenerative Medicine
Time: 13:30-17:10, November 1, 2019 (Friday); Place: Room 625&626, 6th Floor, DICC

Chair	*Dr. Igor I. Katkov,* Chief Scientific Officer, Stem Cell Research Center, Sanford-Burnham Institute for Medical Research, USA
Co-Chair	*Dr. Abhijit Bopardikar,* Director, ReeLabs Private Limited; Joint Secretary, Stem Cell Society of India, India

13:30-13:35	Chair’s Introduction
13:35-13:55	Keynote Speech Title: Challenges and Innovations in Regenerative Medicine Dr. Abhijit Bopardikar, Joint Secretary, Stem Cell Society of India, India
13:55-14:15	Title: Technology and Innovation to Support the Global Scaleup Challenges on the Horizon *Dr. Steven Lynum,* Executive Director, PHC Corporation (Based in USA), Japan
14:15-14:35	Title: Kinetic (Hyperfast and Free of Permeable Cryoprotectants) Vitrification: a Novel Approach for Cryopreservation of Stem Cells for Regenerative Medicine *Dr. Igor I. Katkov,* CSO, CELLTRONIX, USA
14:35-14:55	Title: Stem Cells for Aesthetic and Therapeutic Use Dr. Michael Lim Ming Soon, Founder, Prime Genesis Pte. Ltd., Singapore
14:55-15:15	Title: Vitrification of Embryos and Oocytes for Fertility Preservation in Cancer Patients Dr. Keiichi Kato, General Director, Kato Ladies Clinic, Japan
15:15-15:30	Coffee Break
15:30-15:50	*Title:* Rapid ELISA Using a Film-Stacked 3D-Structure *Dr. Ming Yang,* Professor, Tokyo Metropolitan University, Japan
15:50-16:10	*Title:* IceBattery® Systems a Next Generation Borderless Medical Cold Chain Logistics Technology for the Global Market Dr. Pankaj Garg, Founder, Innovation Thru Energy Co. Ltd., Japan
16:10-16:30	Title: Remote Management of Biosystems via the Digital Biohologram of the Stem Cell as the Wave Optics Modulated by the Refraction Code in the Scalar Wave Diffraction Grating Dr. Irene Caesar, President, Wave Genome LLC, Russia
16:30-16:50	*Title:* Application of Mesenchymal Stem Cell Exosomes in Ocular Diseases Dr. Xiaorong Li, Director, Tianjin Medical University Eye Hospital, China
16:50-17:10	Title: A Center for Innovative Development and Manufacturing in Cell and GeneTherapy *Dr. Haro Hartounian,* Senior Executive Director, New Jersey Innovation Institute, USA

RMSC 04: Scientific Innovations in Tissue & Organ Engineering
Time: 08:30-12:10, November 2, 2019 (Saturday); Place: Room 615&616, 6th Floor, DICC

Chair	*Dr. Jaime Tisnado,* Professor, VCU Medical Center, USA
Co-Chair	*Dr. Masahiro Iwata,* Professor, Uji Tokushukai Medical Center, Japan

08:30-08:35	Chair’s Introduction
08:35-09:00	*Title:* Delayed Immune Reconstitution after Allogeneic Transplantation Increases the Risks of Mortality and Chronic GVHD Dr. Nelli Bejanyan, Associate Member, Moffitt Cancer Center, USA
09:00-09:25	Title: Interventional Radiologic Management of Trauma to the Central Nervous System *Dr. Jaime Tisnado,* Professor, Virginia Commonwealth University, USA
09:25-09:50	Title: Molecular Detection of Two Major Mutations Causing Two Genetic Diseases, Beta Thalassemia and Cystic Fibrosis *Dr. Pranab Roy,* Senior Consultant, Institute of Child Health, India
09:50-10:15	Title: The Therapeutic Effect and Mechanism of IPFP-MSC Derived Exosomes on Osteoarthritis *Dr. Jiangyi Wu,* Peking University Shenzhen Hospital, China
10:15-10:30	Coffee Break
10:30-10:55	Title: Usefulness of New Method Using Absorbable Sealing Materials and Fibrin Glue to Wound of Partial Glossectomy~Long-term Evaluation and Piled-up Method *Dr. Masahiro Iwata,* Professor, Uji Tokushukai Medical Center, Japan
10:55-11:20	Title: Effects on Periodontal Tissue Regeneration by Conditioned Medium Derived from Gingival Mesenchymal Stem Cells and Periodontal Ligament Stem Cells: A Comparative Study in Rats Dr. Aimei Song, Associate Professor, Shandong University, China
11:20-11:45	*Title:* Engineered Liver-on-a-chip Platform to Mimic Liver Functions *Dr. Xiuli Zhang,* Professor, Soochow University, China
11:45-12:10	*Title:* Regemat 3D: 3D Printing of Medical Devices and Bioprinting *Mr. Jeff,* Head, APG Bio LTD, China

RMSC 05: xLab Regenerative Drug Discovery
Time: 08:30-11:45, November 2, 2019 (Saturday); Place: Room 617&618, 6th Floor, DICC

Chair	*Dr. Willie Chan SaiHo,* Professor, Panbiotic Laboratories, Hong Kong China
Co-Chair	*Dr. Li Huang,* Doctor, Affiliated Taihe Hospital of Hubei University of Medicine, China

08:30-08:35	Chair’s Introduction
08:35-09:00	*Title:* Regenerative Medicine in Neurodegenerative Diseases Dr. Kaili Lin, Senior Scientist, Hong Kong Baptist University, China
09:00-09:25	*Title:* The Past, Present and Future of Regenerative Medicine *Dr. Willie Sai Ho Chan,* Professor, Queen's College, Hong Kong China
09:25-09:50	*Title:* Construction of Screening Platform for Anti-Lung Cancer Metastasis Drugs Based on Circulating Cancer Cells Dr. Zujun Que, Assistant Researcher, Shanghai University of Traditonal Chinese Medicine, China
09:50-10:15	Title: Clinical Pilot Studies of Human Umbilical Cord Mesenchymal Stem Cell Transfusion for Children with Cerebral Palsy *Dr. Li Huang,* Doctor, Affiliated Taihe Hospital of Hubei University of Medicine, China
10:15-10:30	Coffee Break
10:30-10:55	*Title:* CellSOP System Enhances Cell Management Capabilities and Experimental Processes Dr. Miao Sun, CTO, DASHOO, China
10:55-11:20	Title: Implementation of a Nursing Protocol for the Use of Ozonotherapy in Treatment of the Buruli Ulcer *Dr. Antonio Galoforo,* Teacher, University of Pavia, Italy
11:20-11:45	Title: Image Xpress Pico@ Personal High Content Imaging System *Dr. Hanying Du,* Scientist, Molecular Devices, China

RMSC 06: Stem Cell Therapy on Common Diseases
Time: 08:30-11:50, November 2, 2019 (Saturday); Place: Room 625&626, 6th Floor, DICC

Chair	*Dr. Dianrong Gong,* Professor, Liaocheng People’s Hospital, China
Co-Chair	*Dr. Evgenii Germanovich Skurikhin*, Head, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Russia

08:30-08:35	Chair’s Introduction
08:35-08:55	Title: Application of Mesenchymal Stem Cells in Uveitis *Dr. Xiaomin Zhang,* Professor, Tianjin Medical University Eye Hospital, China
08:55-09:15	Keynote Speech Title: The Grim Side of Stem Cell Therapy: Indonesian Experience *Dr. Jeanne Adiwinata,* Professor, University of Indonesia, Indonesia
09:15-09:35	Title: Oxigen-Ozone Therapy in Avascular Necrosis of the Femoral Head *Dr. Francesco Rossetti,* Orthopaedic Surgeon, San Pellegrino Hospital, Italy
09:35-09:55	*Title:* Human Umbilical Cord Blood Mononuclear Cell Therapy by Lateral Atlanto-Occipital Space Puncture for Parkinson’s Disease Patients Dr. Dianrong Gong, Professor, Liaocheng People’s Hospital, China
09:55-10:15	Title: New Generation of Mesenchymal Stem Cells-Based Therapy for Acute Myocardial Infarction: from Bench to Bedside Dr. Yue-Jin Yang, Vice President, Cardiovascular Institute and Fuwai Hospital, China
10:15-10:30	Coffee Break
10:30-10:50	*Title:* Human Embryonic Stem Cell Derived Cardiovascular Progenitors for Heart Regeneration in Preclinical Models *Dr. Lynn Yap,* Senior Scientist, Duke-NUS Medical School, Singapore
10:50-11:10	Title: Endothelial Progenitor Cells as Pathogenetic and Diagnostic Factors, and Potential Targets for Glucagon-like Peptide 1 in Combination with Metabolic Syndrome and Chronic Obstructive Pulmonary Disease Dr. Evgenii Germanovich Skurikhin, Professor, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Russia
11:10-11:30	*Title:* A New Hope for Diabetes: Gplife Advanced Diabetic Support Tablet as an Adjuvant Therapy in Patients with Diabetes *Dr. Shridhar J Pandya,* Managing Director, Gplife Healthcare Pvt Ltd., India
11:30-11:50	*Title:* Evaluation of the Efficiency of Allogeneic Cord Blood Transfusion in Patients with Autism (Preliminary Assessment) *Dr. Tiumina Olga,* Director, Samara Regional Medical Center Dinasty, Russian Federation

RMSC 07: Smart World AI & Smart Materials in RMSC
Time:13:30-17:10, November 2, 2019 (Saturday); Place: Room 615&616, 6th Floor, DICC

Chair	*Dr. Shaohua Ma,* Professor, Tsinghua University, China

13:30-13:35	Chair’s Introduction
13:35-14:00	*Title:* Supporting Biosafety Testing of Advanced Therapy Medicinal Products with Platform Assays and Rapid Methods Dr. Edmund Ang, Principal Scientist, Merck Pte. Ltd., Singapore
14:00-14:25	*Title:* Clinical Grade Biolaminins are the Key for Robust and Repeatable Therapeutic Cell Processing Dr. Kristian Tryggvason, CEO, The Biotechnology Company BioLamina, Sweden
14:25-14:50	Title: Engineering Reproducible Stem Cell Microenvironments with Minimal Interference on Cells *Dr. Shaohua Ma,* Professor, Tsinghua University, China
14:50-15:15	*Title:* The Concept of Distributed Manufacturing for Scaling of Complex Autologous Cell Therapies *Dr. Ram Bedi,* Assistant Professor, University of Washington, USA
15:15-15:30	Coffee Break
15:30-15:55	Title: Recognizing a Nature of the Nerve Impulses as Ionized Photons According to an Innovative Definition of the Electric Current Dr. Salama Abdelhady, Professor, Aswan University, Egypt
15:55-16:20	*Title:* The Roles of Type Ii Alveolar Stem Cells in Radiation-Induced Lung Fibrosis by Tracking Dynamic Phenotypes and Expression of Cell Differentiation Regulators Dr. Jian Tian, Professor, Zhengzhou University and Henan University, China
16:20-16:45	Title: Unicell Life Company and Product Introduction Dr. Xiaoting Sun, Director, Unicell Life Technology Co., Ltd., China
16:45-17:10	Title: Key Points for Biological Sample Preservation, ISBER Best Practices & AABB Accreditation Mr. Gil Edward, General Manager, Abeyatech, LLC, USA

RMSC 08: Endless World of Stem Cells
Time:13:30-17:35, November 2, 2019 (Saturday);Place: Room 617&618, 6th Floor, DICC

Chair	*Dr. Haolin Chen,* Professor, Wenzhou Medical University, China
Co-Chair	*Dr. Jooyoun Lee,* President of R & D Center, Xcell Therapeutics, South Korea

13:30-13:35	Chair’s Introduction
13:35-14:00	*Title:* Regenerative Injection Therapy for Sports Injuries - Clinical Evidence Dr. Suad Trebinjac, Consultant, Al Garhoud Private Hospital, UAE
14:00-14:25	*Title:* GABAergic Synapse Suppresses Innate Immunity via Muscle-Derived Insulin Signalling Dr. Haijun Tu, Professor, Hunan University, China
14:25-14:50	*Title:* Identification and Differentiation of Rat Testicular Stem Leydig Cells in Vitro Dr. Haolin Chen, Professor, Wenzhou Medical University, China
14:50-15:15	*Title:* Extracellular Vesicles Derived from MiR-27b-Overexpressing Bone Marrow Mesenchymal Stem Cells Attenuate Apoptosis and Inflammation of OA in A Rat Model Dr. Hui Qi, Associate Professor, Beijing Jishuitan Hospital, China
15:15-15:30	Coffee Break
15:30-15:55	*Title:* Standard for Characteristics of Adipose Derived Stem Cells Cultivated with Serum Free Defined Media Dr. Jooyoun Lee, Head, Xcell Therapeutics, Korea
15:55-16:20	*Title:* Cancer Stem-Like Cells in Benign Odontogenic Tumors *Dr. Chunmiao Jiang,* Physician, Qingdao University, China
16:20-16:45	Title: Ubiquitination-Mediated Regulation of es Cell Differentiation and Cancer Progression *Dr. Weiwei Zhang,* Senior Scientist, Capital Normal University, China
16:45-17:10	*Title:* Stem/Progenitor Cells and Cell-of-origin for Human Prostate Cance *Dr. Dingxiao Zhang,* Professor, Hunan University, China
17:10-17:35	*Title:* Verteporfin Blocks Clusterin which is Required for Survival of Gastric Cancer Stem Cell by Modulating HSP90 Function *Dr. Jixian Xiong,* Lecturer, Shenzhen University, China

RMSC 09: Anti-aging RMSC-Are RMSC Panaceas or Forever Young Possible
Time: 13:30-16:10, November 2, 2019 (Saturday);Place: Room 625&626, 6th Floor, DICC

Chair	*Dr. Nam-Sun Paik,* Dean, Ewha Womans University Cancer Center Hospital for Women, Korea

13:30-13:35	Chair’s Introduction
13:35-14:00	Title: Clinical Practice and Theory of Human Adult Stem Cells for 8 Years--There are "Sleeping" Stem Cells in Every Tissue that Can be Awakened "Noninvasively in Situ"? *Dr. Chuanjun Liu,* Head, The Plastic Surgery and Anti-aging of Dali University, China
14:00-14:25	*Title:* Managing the Risks of Transforming Regulatory Aging of The Brain into Pathological Aging Dr. Alena Sidenkova, Professor, Ural State Medical University, Russia
14:25-14:50	Title: Current Status of Korean Breast Cancer and New Technology of Oncoplastic Surgery *Dr. Nam-Sun Paik,* Dean, Ewha Womans University Cancer Center Hospital for Women, Korea
14:50-15:15	*Title:* Perinatal Stem Cells Tissue Engineered Cardiovascular Grafts for Corrective Surgery of Congenital Heart Defects *Dr. Mohamed T Ghorbel,* Senior Research Fellow, University of Bristol, UK
15:15-15:30	Coffee Break
15:30-15:50	*Title:* Occurrence and Levels of Potentially Harmful Elements (Phes) in Natural Waters of the Gold Mining Areas of the Kette-Batouri Region of Eastern Cameroon Dr. Michael Shapi, Head, Mangosuthu University of Technology
15:50-16:.10	*Title:* Effects of Transplanted Heparin-Poloxamer Hydrogel Combining Dental Pulp Stem Cells and bFGF on Spinal Cord Injury Repair Dr. Abdullkhaleg Ali Albashari, Scientist, Wenzhou Medical University, China

RMSC 10: Cancer Stem Cell Therapy
Time: 08:30-10:15, November 3, 2019 (Sunday); Place: Room 615&616, 6th Floor, DICC

Chair	*Dr. Ningsun Yang,* Professor, Academia Sinica, Taiwan

08:30-08:35	Chair’s Introduction
08:35-09:00	Title: Zfra Blocks Cancer Growth by Suppressing Cancer Stem Cell Proliferation Dr. Nan-Shan Chang, Professor, National Cheng Kung University, Taiwan China
09:00-09:25	Title: Managing Neurotoxicity beyond Corticosteroids for the FDA-approved CAR-T Cell Therapies: Current Challenges and Future Directions Dr. Aleksandr Lazaryan, Associate Member, Moffitt Cancer Center, USA
09:25-09:50	Title: Developing Immune Cell-Based Therapeutics or Vaccines against Metastatic Cancers Dr. Ningsun Yang, Professor, Academia Sinica, Taiwan
09:50-10:15	*Title:* Retrospective Analysis of the Impact of Anthracycline Dose Reduction and Chemotherapy Delays on the Outcomes of Early Breast Cancer Molecular Subtypes *Dr. Sigita Liutkauskiene,* Associate Professor, Lithuanian University of Health Sciences, Lithuania

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